2026-09-22T01:38:59Zhttps://api.repository.cam.ac.uk/server/oai/requestoai:www.repository.cam.ac.uk:1810/3177232021-06-22T09:23:54Zcom_1810_213729com_1810_256065col_1810_219485
Engineering the Plasmon Resonance of Gold Nanoshells for Biological Applications
10.17863/CAM.64837
Taha, Nesrine Nagui
Within this research I have investigated the effect of pH and the ratio of gold to silica colloids on the
formation of nanoshell precursor seed particles thereby leading to the optimization of the process
by which gold nanoshells are formed. With a focus on nanoshells for the thermal ablation of cancer
cells, 104.5 nm core shell particles having a peak resonance at 940 nm were formed. The study also
presents two new methods by which ‘textured’ nanoshells may be formed for use in applications
such as substrates for Surface Enhanced Raman Spectroscopy. The thesis has also investigated the
effect of temperature on the surface morphology of the gold nanoshells. Investigations in this
respect have led to the finding that the formation of nanoshells at an elevated temperature allows
for the generation of nanoshells having a smooth surface morphology, irrespective of the shell
thickness.
University of Cambridge
2010-02
Thesis
masters
MPhil
en
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nanoshells
Spectroscopy
Gold nanoshells
multifunctional nanoparticles
GBMF
Glioblastoma multiform
seed nanoparticle formation
plasmon resonance
detailed gold nanoshell formation protocol