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<article article-type="review-article" dtd-version="1.1" xml:lang="en" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><front><journal-meta><journal-id journal-id-type="publisher-id">NRO</journal-id><journal-id journal-id-type="nlm-ta">Neuroscientist</journal-id><journal-title-group><journal-title>The Neuroscientist</journal-title></journal-title-group><issn pub-type="ppub">1073-8584</issn><issn pub-type="epub">1089-4098</issn><publisher><publisher-name>SAGE Publications</publisher-name><publisher-loc>Sage CA: Los Angeles, CA</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.1177/1073858420907591</article-id><article-id pub-id-type="publisher-id">10.1177_1073858420907591</article-id><article-categories><subj-group subj-group-type="heading"><subject>Reviews</subject></subj-group></article-categories><title-group><article-title>Dopamine, Prediction Error and Beyond</article-title></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9619-6583</contrib-id><name><surname>Diederen</surname><given-names>Kelly M. J.</given-names></name><xref ref-type="aff" rid="aff1-1073858420907591">1</xref><xref ref-type="corresp" rid="corresp1-1073858420907591"/></contrib><contrib contrib-type="author"><name><surname>Fletcher</surname><given-names>Paul C.</given-names></name><xref ref-type="aff" rid="aff2-1073858420907591">2</xref><xref ref-type="aff" rid="aff3-1073858420907591">3</xref><xref ref-type="aff" rid="aff4-1073858420907591">4</xref></contrib></contrib-group><aff id="aff1-1073858420907591"><label>1</label>Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK</aff><aff id="aff2-1073858420907591"><label>2</label>Department of Psychiatry, University of Cambridge, Cambridge, UK</aff><aff id="aff3-1073858420907591"><label>3</label>Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK</aff><aff id="aff4-1073858420907591"><label>4</label>Wellcome Trust MRC Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK</aff><author-notes><corresp id="corresp1-1073858420907591">Kelly M. J. Diederen, Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, De Crespigny Park, London SE5 8AF, UK. Email: <email>kelly.diederen@kcl.ac.uk</email></corresp></author-notes><pub-date pub-type="epub"><day>26</day><month>4</month><year>2020</year></pub-date><volume>27</volume><issue>1</issue><fpage>30</fpage><lpage>46</lpage><permissions><copyright-statement>© The Author(s) 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder content-type="sage">SAGE Publications</copyright-holder><license><ali:license_ref start_date="2020-04-26" xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0/</ali:license_ref><license-p>This article is distributed under the terms of the Creative Commons Attribution 4.0 License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (<ext-link ext-link-type="uri" xlink:href="https://us.sagepub.com/en-us/nam/open-access-at-sage">https://us.sagepub.com/en-us/nam/open-access-at-sage</ext-link>).</license-p></license></permissions><abstract><p>A large body of work has linked dopaminergic signaling to learning and reward processing. It stresses the role of dopamine in reward prediction error signaling, a key neural signal that allows us to learn from past experiences, and that facilitates optimal choice behavior. Latterly, it has become clear that dopamine does not merely code prediction error size but also signals the difference between the expected value of rewards, and the value of rewards actually received, which is obtained through the integration of reward attributes such as the type, amount, probability and delay. More recent work has posited a role of dopamine in learning beyond rewards. These theories suggest that dopamine codes absolute or unsigned prediction errors, playing a key role in how the brain models associative regularities within its environment, while incorporating critical information about the reliability of those regularities. Work is emerging supporting this perspective and, it has inspired theoretical models of how certain forms of mental pathology may emerge in relation to dopamine function. Such pathology is frequently related to disturbed inferences leading to altered internal models of the environment. Thus, it is critical to understand the role of dopamine in error-related learning and inference.</p></abstract><kwd-group><kwd>dopamine</kwd><kwd>prediction errors</kwd><kwd>brain</kwd><kwd>psychiatry</kwd><kwd>learning</kwd></kwd-group><custom-meta-group><custom-meta><meta-name>typesetter</meta-name><meta-value>ts1</meta-value></custom-meta></custom-meta-group></article-meta></front></article>